People often refer to mitochondria as the powerhouses of the cell. Their main function is to generate the energy necessary to power cells, but they are also involved in cell signaling and death.

A new study in mice suggests that dysfunctional mitochondria may change the gut microbiome and thus drive Crohn's disease. When you purchase through links on our site, we may earn an affiliate ...

Mitochondria are responsible for producing and providing energy to our bodies, especially in organs such as the heart, brain, and muscles, which require high-energy production. These organs ...

As direct descendants of ancient bacteria, mitochondria have always been a little alien. Now a study shows that mitochondria are possibly even stranger than we thought. The study, titled "Somatic ...

Somatic nuclear mitochondrial DNA insertions are prevalent in the human brain and accumulate over time in fibroblasts. PLOS Biology , 2024; 22 (8): e3002723 DOI: 10.1371/journal.pbio.3002723 Cite ...

Abstract: Accurate and robust segmentation of mitochondria from electron microscopy images plays a critical role in understanding cellular functions. While effective, learning-based approaches require ...

Mitophagy, a selective form of autophagy, maintains dynamic homeostasis of cells through targeting long-lived or defective mitochondria for timely clearance and recycling. Dysfunction in mitophagy is ...

Mitochondria appear to communicate and cooperate with one another, both within and between cells. Biologists are only just beginning to understand how and why. During his doctoral research on the ties ...

That’s the best hypothesis to date for how the cellular components, or organelles, known as mitochondria came to be. Today, trillions of these bacterial descendants live within our bodies ...

In this study, we were able to perform gene editing in the mitochondrial DNA by appending an NADH-ubiquinone oxidoreductase chain 4 (ND4) targeting guide RNA to an RNA transport-derived stem loop ...

Here, we discover that the optic atrophy–associated mitochondrial disease gene TMEM126A plays a role in the assembly of the first enzyme of the respiratory chain, complex I. Critically, we show that ...