Medscape2 天
Current Management of Patients With Nonalcoholic Fatty Liver Disease
This study was a multipurposed review, which included discussion of recent studies investigating the cellular and genetic basis of these diseases, the pathogenesis of NAFLD and the current ...
Nature8 年
Reduced circulating levels of sTWEAK are associated with NAFLD and may affect hepatocyte ...
Because of the burden of NAFLD in obesity, its association with insulin resistance and the potential role of TWEAK in the liver, we investigated the contribution of TWEAK to the pathogenesis of NAFLD.
The Lancet8 年
Pathogenesis and novel treatment options for non-alcoholic steatohepatitis
In this Review, we discuss the pathogenesis, treatment evaluation, existing therapies, and potential new treatments for NASH. The pathogenesis of NAFLD and the factors that promote progression from ...
gut.bmj1 个月
miRNAs and NAFLD: from pathophysiology to therapy
unige.ch Non-alcoholic fatty liver disease (NAFLD) is associated with a thorough reprogramming of hepatic metabolism. Epigenetic mechanisms, in particular those associated with deregulation of the ...
The Lancet4 年
Pathogenesis and novel treatment options for non-alcoholic steatohepatitis
In this Review, we discuss the pathogenesis, treatment evaluation, existing therapies, and potential new treatments for NASH. The pathogenesis of NAFLD and the factors that promote progression from ...
Microbiome signatures can predict nonalcoholic fatty liver disease with high accuracy
Nonalcoholic fatty liver disease (NAFLD) affects up to 40% of the population in western countries and is one of the most ...
Medscape2 天
What Advice Should Be Given to Patients With NAFLD About the Consumption of Alcohol?
Nat Clin Pract Gastroenterol Hepatol. 2009;6(1):18-19. Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases in the Western world. NAFLD is associated with chronic ...
Frontiers1 年
The role of gut microbiota in the occurrence and progression of non-alcoholic fatty liver ...
A decrease in microbial alpha diversity can potentially contribute to the pathogenesis and progression of diseases (Wenhui et al., 2022). Our ROC analysis using alpha diversity as a predictor yielded ...
来自MSN12 天
Microbiome Signatures Can Predict Nonalcoholic Fatty Liver Disease
Using medical data from more than 1,200 people, specific microbiome signatures have been identified that allow precise ...
gut.bmj2 年
IDDF2022-ABS-0049 GPR35 deficiency aggravates NAFLD via remodeling the GUT microbiome
Background Genetic and environmental factors increase susceptibility to non-alcoholic fatty liver disease (NAFLD), and the gut microbiome is increasingly implicated. However, the crosstalk of gut ...
Frontiers29 天
Targeting immune cellular populations and transcription factors: unraveling the therapeutic ...
Single-cell RNA sequencing and spatial transcriptomics furthered our understanding of NAFLD pathophysiology and JQF’s treatment mechanisms. Results: Our findings initially revealed significant ...