Cardiac hypertrophy is the abnormal enlargement, or thickening, of the heart muscle, resulting from increases in cardiomyocyte size and changes in other heart muscle components, such as ...

New therapies to blunt this process include targeting enzymes below the cell membrane that serve as strategic nodes for hypertrophy regulation. Rho kinase (ROCK) is activated in cardiac ...

1 Inner Mongolia Key Laboratory of Disease-Related Biomarkers, The Second Affiliated Hospital, Baotou Medical College, Baotou, China 2 School of Basic Medicine, Baotou Medical College, Baotou, China ...

Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiovascular condition. It is the leading cause of sudden ...

HCM is typically characterized by asymmetric myocardial hypertrophy, which is often associated with diastolic dysfunction, LV outflow tract obstruction and mitral regurgitation. Myocardial cell ...

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A 36-year-old man died last fall at the Spokane County Jail from a heart problem, according to the Spokane County Medical ...

The cause of death for an inmate who was found unresponsive in his cell at Spokane County Jail has been determined.

For children with severe hypertrophic cardiomyopathy caused by gain-of-function RAS/mitogen-activated protein kinase (MAPK) mutations (RASopathy), trametinib reduces mortality and morbidity.

Cardiac arrest can have several causes. Heart attack is a common cause. Other conditions may also disrupt the heart's rhythm and lead to cardiac arrest. Hypertrophic cardiomyopathy (HCM)—or a ...