Thus, G-protein-coupled receptors can regulate NMDA receptor function indirectly through a PKC-dependent activation of the non-receptor tyrosine kinase (Src) signaling cascade. You have full ...

Fresh medium was replaced for one hour immediately before assaying receptor function as described 35. Briefly, cells were incubated in Dulbecco's phosphate buffered saline containing 1 mM IBMX for ...

This highlights the need for further optimization of γδ T cell products to improve anti-tumor potency, such as the increased targeting induced by the expression of a chimeric antigen receptors (CAR ..

Istituto di Chimica Farmaceutica e Tossicologica, Università degli Studi di Milano, Viale Abruzzi 42, 20131 Milano, Italy; Pharmaceutical Chemistry, Institute of Pharmacy, University of Würzburg, Am ...

† Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, Kentucky 40536, United States ‡ Department of Pharmaceutical Sciences, ...

Thermal receptors called ionotropic receptors (IRs), specifically IR25a and IR21a, function in cool temperature-sensing neurons in larval heads known as dorsal organ cool cells (DOCCs), to mediate ...

Muscarinic receptor (mAChR) transmission modulates intrinsic excitability and allows for ... Neuronal activity is shaped by both synaptic transmission and intrinsic excitability. Changes in either of ...