Sequestration does not affect the monomer steady-state value Profilin is a major regulator of actin assembly that binds ATP–G-actin with high affinity. Profilin–actin exclusively feeds barbed ...

The dynamic interchange between monomeric G-actin and polymeric F-actin filaments is fundamental to cell motility and cytokinesis. Actin filament dynamics is regulated by numerous actin-binding ...

"That's the fast end. The loose connection within the actin polymer allows incoming actin monomers to have access to a binding site, such that it can make a new connection quickly and the ...

Cofilin encourages depolymerization by promoting dissociation of actin monomers from the actin chain. Detection can be achieved using one of two antibodies (Anti-Cofilin antibody or its phospho S3 ...

The assembly of this cytoskeleton is controlled at many levels including globular actin monomers (G-protein) undergoing reversible polymerization into actin polymers and the superorganization of ...

Among the novel advances are characterization of the normal stepping across 13 actin monomers and the not-infrequent "misstepping" across 11 monomers that causes the myoV to rotate along the ...

"In that experiment, we took two myosin VI monomers and 'zippered' their tops together to form a dimer – which then walked along the actin," Selvin said. "Some researchers thought that by ...

However, this role is not very well understood. Here we create a gel with polymerizing actin monomers which contains polystyrene beads. The gel is imaged over a set time period using brightfield ...

The driving force for cell migration is produced by a protein called actin. Actin monomers act as building blocks by polymerising into rod-like filaments that push the leading edge of the cell ...