Sequestration does not affect the monomer steady-state value Profilin is a major regulator of actin assembly that binds ATP–G-actin with high affinity. Profilin–actin exclusively feeds barbed ...

This reaction is strongly kinetically disfavoured by the presence of proteins that sequester actin monomers within cells. Thus, protein cofactors that promote actin filament nucleation are ...

Among the novel advances are characterization of the normal stepping across 13 actin monomers and the not-infrequent "misstepping" across 11 monomers that causes the myoV to rotate along the ...

"In that experiment, we took two myosin VI monomers and 'zippered' their tops together to form a dimer – which then walked along the actin," Selvin said. "Some researchers thought that by ...

Actin monomers act as building blocks by polymerising into rod-like filaments that push the leading edge of the cell forward. The polymerisation of the actin filaments must be balanced by ...