The U.S. Food and Drug Administration has issued warning letters to two feed mills, Gilman Co-Op Creamery in Gilman, Minnesota, and Farmers/Ranchers Cooperative Association of Ainsworth in Ainsworth, ...
The ionophores approved for use in cattle include monensin (Rumensin®), lasalocid (Bovatec®) and laidlomycin propionate (Cattlyst®). Although all ionophores can be toxic, this article will focus on ...
增强靶向性:通过合理设计,可以使 CY3-Monensin 与特定的靶点或细胞表面受体具有特异性结合能力,从而实现药物的靶向递送,提高药物在病变部位的浓度,减少对正常组织的损伤。 改善药物性质:CY3 的连接可能会在一定程度上改善莫能菌素的物理化学性质 ...
For a cow to feed a calf and retain its own body condition requires a good solid intake of essential nutrients. First-calf ...
This study on mouse Ly49 receptors expressed on natural killer (NK) cells shows that Ly49A, in the presence of the corresponding MHC Class I allele, can lead to NK cell licensing, thereby providing ...
After a 2 h incubation at 37°C in a 5% CO 2 atmosphere, Brefeldin A (BFA; Sigma; final concentration 3 μg/ml) and Monensin (BioLegend, San Diego, USA, final concentration 1X) were added to inhibit ...
Golgi Stop (BD Biosciences) (monensin) was added following the manufacturer’s protocol. After the incubation, cells were collected, washed, and labeled with anti-CD3-PerCP/Cy5.5 (Biolegend, clone SK7) ...
非经典途径的影响:研究人员还研究了非经典途径对 TFEB 穿梭动力学的影响。用 Monensin 处理细胞激活 GABARAP - CASM 途径后,TFEB 转位到细胞核,但没有 “过冲” 现象,这表明 “过冲” 现象是经典 mTORC1 抑制介导的转位途径所特有的。 研究结论和讨论部分指出 ...
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