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News-Medical.Net on MSNMelanoma’s excessive mitochondrial dependence becomes a therapeutic vulnerabilityResearchers have discovered that the most aggressive melanomas, the deadliest form of skin cancer, overactivate two key ...
In this study, a mouse model with a knockout of the mitochondrial tRNA modification enzyme (Mto1) exhibited defective mitochondrial protein synthesis, revealing a previously unknown molecular ...
A new technique that alters protein production in mitochondria could help researchers understand mitochondrial diseases as ...
Mitochondrial degeneration was suppressed by lifespan-extending nutritional interventions and by eight longevity mutations, which are all known to reduce cytosolic protein synthesis.
A team of researchers has uncovered a previously unrecognized role of mitochondrial protein synthesis in the maintenance of intracellular iron distribution. Disruption of this process was found to ...
RNA modification is responsible for the disruption of mitochondrial protein synthesis in Alzheimer's disease. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2024 / 04 ...
Mitochondrial pathways help melanoma cells become aggressive, and some currently available drugs target these pathways.Researchers have discovered ...
Surprising features of mitochondrial protein synthesis uncovered. Jun 10, 2020. Researchers sniff out potential Leigh syndrome treatment. Jul 18, 2016.
MFN2 has long been recognized for its role in mitochondrial fusion. The researchers now uncovered an additional, unexpected function of MFN2 in maintaining protein quality within cells.
A deficiency in mitochondrial protein synthesis, due to the knockout of the MTO1 gene in hematopoietic cells, disrupts intracellular iron distribution, leading to fetal anemia.
A team of researchers in Kumamoto University uncovered a previously unrecognized role of mitochondrial protein synthesis in the maintenance of intracellular iron distribution. Disruption of this ...
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