In flies defective for axonal transport of mitochondria, the authors report the upregulation of one subunit, the beta subunit, of the heterotrimeric eIF2 complex via mass spectroscopy proteome ...

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1 IDR/Research and Education Network, Westmead, NSW, Australia 2 Faculty of Medicine and Health, School of Medical Sciences, The University of Sydney, Sydney, NSW, Australia Neural differentiation ...

The human brain is a complex powerhouse, responsible for orchestrating thoughts, emotions, and memories. Its nerve cells ...

Mitochondria are crucial organelles for cellular homeostasis, regulating processes such as ATP production, reactive oxygen ...

However, reperfusion can induce neuronal death, known as cerebral reperfusion injury, for which effective therapies are lacking. Accumulating data supports a paradigm whereby cerebral ...

Mitochondria organelles came from primordial bacterial endosymbionts and still preserve distinct genes for important functions like making ATP. To speed the emerging therapeutic research into the ...

MDPs, such as humanin and the newly identified SHMOOSE, are being studied for their ability to enhance mitochondrial function and protect against neuronal damage. One of the key findings in recent ...