One significant area of research has been the role of mineralocorticoid receptors (MR) in ethanol-induced hypertension. A study found that blocking these receptors prevented the increase in blood ...

Innate immunity is the first defense system against invading pathogens. Toll-like receptors (TLRs) are well-defined pattern recognition receptors responsible for pathogen recognition and induction of ...

AR = Androgen receptor; ER = Estrogen receptor; GR = Glucocorticoid receptor; MR = Mineralocorticoid receptor; PR = Progesterone receptor. The relative binding affinity (%) of the main progestins ...

Here, we provide an optimized approach for TCR clone selection that capitalizes on recent technological advances in the single cell sequencing field that combine analysis of cellular heterogeneity of ...

To overcome this detection problem, adoptive transfer of a cohort of T cells purified from T cell receptor (TCR) transgenic donors has been extensively used ... B) Projection of the three sequenced ...

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In this article the role of a family of pH-sensing G protein-coupled receptors (GPCRs) in tumor biology is reviewed. Recent studies show that the pH-sensing GPCRs, including GPR4, GPR65 (TDAG8), GPR68 ...

Deoxycorticosterone acetate-salt hypertension (DOCASH) and sham rats were prepared following previously established methods 1; vasoconstriction and western blot experiments followed standard protocols ...