这款试剂盒用的是TMR（四甲基罗丹明）荧光团标记的神经酰胺（Ceramide），它能被细胞吞噬进入并迅速定位到高尔基体。高尔基体是细胞内“快递中心”，负责蛋白加工、分拣、包装和运输。TMR 发出红色荧光，一照就亮，定位非常精准。 用途： 主要用来观察 ...

Calcein-AM是一种可对活细胞进行荧光标记的细胞染色试剂，由于在Calcein的基础上加强了疏水性，因此Calcein-AM能够轻易穿透活细胞膜。当其进入到细胞质后，酯酶会将其水解为Calcein留在细胞内，发出强绿色荧光，Calcein的激发和发射波长分别为490nm和515nm。 Calcein AM ...

Background Fibrolamellar carcinoma (FLC), a rare and fatal liver cancer lacking effective drug therapy, is driven by the DNAJ ...

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discussed a variety of cell viability assays in detail, including staining exclusion (e.g., Taipan blue staining), colorimetric assays ... Morphological observation assesses cell damage by directly ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. During meiosis, at least one crossover is ...

This study provides valuable findings on the role of site-specific DNA methylation changes during spermatogenesis and their contribution to paternal epigenetic inheritance. The study proposes that ...

Shihabeddin et al utilized single-cell RNA-Seq analysis of adult P23H zebrafish animals to identify transcription factors (e2fs, Prdm1a, Sp1) expressed selectively in neural progenitors and immature ...