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Microarrays have taken the process a step further, providing greater ease and speed of detection. CombiMatrix recently launched the Influenza A Research Microarray to detect and type flu strains.
Here we describe lentivirus-infected cell microarrays for the high-throughput screening of gene function in mammalian cells. To create these arrays, we cultured mammalian cells on glass slides ...
Once read, the results provide some insight into gene expression patterns. Yet this more modern version of microarrays didn’t come about until the late 1990s and early 2000s. Traveling back 41 ...
Small molecule microarrays allow screening of biomolecules such as peptides and carbohydrates. By immobilizing these small molecules on a microarray, interactions can be quickly assessed through a ...
As costs become less prohibitive and methods become simpler and more widespread, researchers are choosing NGS over microarrays for more of their genomic applications.Rising maturity in NGS systems ...
Cell-based technologies for printing protein microarrays are faced with poor protein expression, protein insolubility, improper folding and poor shelf life. Cell-free expression-based protein ...
In each type of cell, like a muscle cell or a skin cell, different genes are expressed (turned on) or silenced (turned off). If the cells that are turned on mutate, they could—depending on what ...
Response to Neoadjuvant Chemotherapy Combined With Regional Hyperthermia Predicts Long-Term Survival for Adult Patients With Retroperitoneal and Visceral High-Risk Soft Tissue Sarcomas ABSTRACT: ...
001), likely because microarrays work on degraded tissue. The CMA results included many benign variants and also more aneuploids and pathogenic CNVs (8.3% vs 5.8%; P = .007) than did karyotyping.
However, we lack a comprehensive understanding of all genes that are aberrantly expressed in human cancer. Recently, DNA microarrays have been used to obtain global views of human cancer gene ...
Companies in the microarray sector are trying to take the technology out of core facilities and put it into the hands of individual researchers by developing technologies such as smaller, less-costly ...
In the 25 June Proceedings of the National Academy of Sciences George Dimopoulos and colleagues report the use of first-generation cDNA microarrays for expression profiling analysis of the mosquito ...
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