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揭秘帕金森病:基底前脑如何 “搅乱” 睡眠与认知?
他们通过研究发现,在 PD 患者中,Ch4(基底核 Meynert 的胆碱能成分)前部体积减少及其与默认模式网络(DMN)异常增加的功能连接,与整体睡眠质量差密切相关;而 Ch4 后部体积减少则与认知功能下降有关。这一发现揭示了 BF 胆碱能系统在 PD 患者睡眠和认知 ...
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