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The mevalonate (MVA) pathway is an important metabolic pathway implicated in multiple aspects of tumorigenesis. In this study, we provided evidence that p53 induces the expression of a group of ...
Deficiency in mevalonate kinase (MVK ... Pggt1b or a constitutively active form of p110δ (E1121K) 23. Expression of E1121K, but not wild-type p110δ, completely abrogated LPS-induced IL-1β ...
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