One significant area of research has been the role of the methylenetetrahydrofolate reductase (MTHFR ... such as cystathionine β-synthase (CBS) and serine hydroxy-methyltransferase (SHMT1 ...

A literature review was performed to collect information on the role of pharmacogenetics in six proposed teratogenic mechanisms associated with drug use during pregnancy: folate antagonism ...

Deprivation of both serine and glycine is required to evaluate the role of extracellular serine, as glycine can be converted to serine via the enzyme serine hydroxymethyltransferase (SHMT) 39. The ...

8 DHF indicates dihydrofolate; MTHFR, methylenetetrahydrofolate reductase; SAH, subarachnoid hemorrhage; SAM, S‐adenosylmethionine; and THF, tetrahydrofolate. Beyond examining the intermediary ...

Disclosure: The author has no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials ...

State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory on Metabolic & Developmental Sciences, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, ...