Chronic inflammatory bowel diseases (IBD), such as ... A key issue in treating IBD is the profound disruption of the metabolic interaction between the body and the microbiome—the community ...

enhancing PTH peptide efficacy in vitro and in vivo This study identifies FABP4 as driver of postmenopausal osteoporosis and shows that targeting FABP4 with a small-molecule inhibitor or bone ...

“The most basic difference is that Crohn’s disease can involve the entire GI tract, from the mouth all the way down to the anus, whereas ulcerative colitis is restricted to the colon,” says ...

The gut microbiome plays an important role in the protection against various systemic diseases. Its metabolic products profoundly influence a wide range of pathophysiological events, including the ...

Inflammatory bowel disease is a chronic ... colon and terminal ileum; and ulcerative colitis, which is a mucosal inflammation involving the rectum and colon. Metabolic enzymes of the tricarboxylic ...

When people hear the disease 'Inflammatory Bowel Disease' (IBD), they usually think of stomach pain, frequent bathroom trips, and digestive problems. What is less well-recognised but equally ...

When it's not only jitters before examinations, but something more serious and long-term? Doctors are becoming concerned about a rising incidence of paediatric and adolescent Inflammatory Bowel ...

The proper frequency of these blood tests depends on your age and personal health status -- the most important thing is to ...

More information: Yufeng Li et al, Metagenomic analysis revealing links between age, gut microbiota and bone loss in Chinese adults, npj Metabolic Health and Disease (2025). DOI: 10.1038 ...

The treatment landscape of Inflammatory Bowel Disease (IBD) has undergone a significant transformation over the past two decades. Historically, therapeutic strategies primarily focused on ...

Janssen-Cilag Limited has received approval from the Medicines and Healthcare products Regulatory Agency (MHRA) for guselkumab (Tremfya) to treat Crohn's disease and ulcerative colitis (UC).