This useful manuscript describes cryo-EM structures of archaeal proteasomes that reveal insights into how occupancy of binding pockets on the 20S protease regulates proteasome gating. The evidence ...

In the peripheral blood of humans, the B cell compartment can be divided into four major subsets on the basis of CD27 and IgD expression; naive/transitional (CD27-IgD+), double negative (CD27-IgD), ...

A new study suggests fat cells keep a memory of previous weight gain, which may help to explain why this happens. When you purchase through links on our site, we may earn an affiliate commission.

Please provide your email address to receive an email when new articles are posted on . Memory B cells increased at week 2 after belimumab initiation and returned toward baseline by week 52.

126.com Objectives A population of atypical memory B cells (AtMs) are greatly expanded in patients with active lupus, but their generation and pathophysiological roles are poorly defined. The aim of ...

During influenza infection, both Tfh and B cells are present at germinal centers in the lymph nodes that drain the lungs. Class-switched memory B cells that are primed against the influenza virus ...

In immunology, a profusion of different cell surface markers is used to identify and separate immune cell types. In the novel memory B cell subset, FcRL5 acts as a surrogate marker for positive ...

These effector memory B cells appear to be poised for a rapid serum antibody response upon secondary challenge one year later, Anoma Nellore, M.D., Fran Lund, Ph.D., and colleagues at the University ...

Memory B cells play a critical role to provide long-term immunity after a vaccination or infection. In a study published in the journal Immunity, researchers describe a distinct and novel subset ...

In a recent study posted to the bioRxiv* preprint server, a team of researchers examined the memory B cell repertoire of individuals immunized with three doses of mRNA-based coronavirus disease ...

Vaccine breakthrough cases showed lower memory B cell frequencies against SARS‐CoV‐2 receptor‐binding domain (RBD). Compared to plasma antibodies, antibodies secreted by memory B cells retained a ...