The pregnancy had been full term and unremarkable. There was no history of maternal virilization or administration of progestational agents. The family history was unremarkable. At birth this ...

Virilization manifests as pseudohermaphroditism in female infants, with hirsutism and acne in the mother; the maternal indicators resolve following delivery. To date, only seven males and seven ...

There was no maternal virilization during pregnancy, and he had no skeletal or genital abnormality. Thus, he was initially diagnosed as having nonclassical 21-hydroxylase deficiency (21-OHD).