（编辑推荐）本文系统阐述了肥大细胞（Mast cells, MCs）的生理功能及其在肥大细胞增多症（Mastocytosis）中的病理机制，涵盖WHO分类标准（如惰性系统性肥大细胞增多症indolent SM、侵袭性SM等），并解析MCs激活通路与新型靶点，为临床诊疗提供重要参考。 肥大细胞 ...

Systemic mastocytosis is a disease where too many abnormal mast cells (a type of white blood cell) build up in your skin and other organs. You might get a variety of symptoms, including itchy skin ...

Mastocytosis is a rare condition where an excessive amount of mast cells gather in the organs and tissues of the body. It can affect the skin, lymph nodes, bone marrow, and other organ systems.

If you have systemic mastocytosis, your health care provider may recommend a medicine to treat it. One such medicine is Ayvakit (avapritinib), an oral tablet. Systemic mastocytosis is a rare ...

DelveInsight’s, “Systemic Mastocytosis Pipeline Insight, 2025,” report provides comprehensive insights about 8+ companies and ...

Systemic mastocytosis is a rare health condition in which too many mast cells (a type of immune system cell) build up in the body, causing allergic reactions and other health issues. This disorder ...

What Is Advanced Systemic Mastocytosis? Mast cells, found in connective tissue throughout the body, are a type of white blood cell that helps the immune system function properly and protect ...

Cutaneous mastocytosis is one of two types of mastocytosis, a rare disorder in which too many mast cells — a type of white blood cell that helps the immune system function properly ...

Systemic mastocytosis (SM), a rare blood illness that causes particular immune cells, called mast cells, to accumulate in several places of the body, was the unexpected diagnosis made after more ...

Sanofi agrees to buy Blueprint Medicines for $9.5 billion, enhancing its rare disease treatments and immunology drug pipeline with FDA-approved Ayvakit ...