As another example of an RTK with a central role in both malignant and non-malignant diseases, the fibroblast growth factor receptor and its downstream signalling pathway have been implicated both ...

For example, the loss of TP53, often seen with disease progression, 21 provokes stem-cell-like transcriptional programs. 69, 70 Other oncogenes may also afford leukemogenic potential to committed ...

Patients with 'cancer of unknown primary origin' have metastatic malignant disease without an identifiable primary site. For patients with this condition the type of tumour, the extent of its spread, ...

For example the ESMO guidelines recommend a PET/CT and brain MRI for patients with single-site or oligometastatic CUP. ... This could also consider the role of the GP and how the NICE guideline on ...

Malignant bone marrow disease: New hope for MPN patients. ScienceDaily. Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2019 / 02 / 190205102523.htm. University of Veterinary ...

While an estimated 14.1 million people in the world are living with cancer, the origins of the devastating disease have remained ... definitive evidence of malignant cancer.