Chronic inflammation is the common pathological basis for such age-associated diseases as cardiovascular disease, diabetes, cancer and Alzheimer’s disease. A multitude of bodily changes occur ...

Fat crystals trigger chronic inflammation Previously unknown disease mechanism Date: August 24, 2020 ... To this end, the researchers examined certain immune cells of the mouse, the macrophages.

The stressed macrophages then send out an "SOS" signal by releasing a substance called MCP-1 (monocyte chemoattractant ...

Tiny cells which have the ability to trigger the body's immune responses could be crucial to research into a number of chronic medical conditions, scientists have suggested. Dr Andrew Foey, from ...

In addition, our results reveal a vulnerability of macrophages that contributes to chronic inflammatory diseases and that could be exploited therapeutically for the treatment of conditions ...

SLAMF7 super-activated macrophages drive inflammation in autoimmune and infectious disease. A) Volcano plot from Fig. 1A highlighting genes from the “SLAMF7-High Macrophage Signature,” the ...

Macrophage protein has major role in inflammation Date: November 3, 2010 Source: University of California - San Diego Summary: Researchers have discovered that a multi-tasking protein called FoxO1 ...

“The macrophage will localize wherever the inflammation is in the brain, so you can see the location of the inflammation. The primary objective, though, is to see if there is inflammation; the ...

Schematic summarising the cellular and molecular features of chronic inflammation identified from cross-sectional assessments of functionally distinct tendons. Macrophages in diseased tendons show a ...

Immunotherapy. 2011;3(10):1265-1274. IL-1 Mediates inflammatory cell accumulation in the TME IL-6 Modifies gene expression through epigenetic effects, transcription factor control and miRNA ...