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Autophagy, a highly conserved cellular process, is pivotal in degrading and recycling cellular components to support metabolism. Recent studies have highlighted the critical role of neural ...
Several autophagy pathways operate within a cell, including macroautophagy, microautophagy and chaperone-mediated autophagy. Liver fibrosis is a consequence of the sustained inflammatory processes ...
这篇综述系统探讨了溶酶体(lysosome)在衰老调控中的核心作用,提出其通过维持自噬(macroautophagy)和蛋白质稳态(proteostasis ...
撰文丨王聪编辑丨王多鱼排版丨水成文从古至今,人类从未停止对“长生不老”追寻和探索。而在过去十年间,我们见证了衰老研究领域发生了巨大变化。通过研究驱动衰老的生物学过程,研究人员旨在开发能够延长生命质量和健康寿命的干预措施。此外,研究人员还对不同年龄段健 ...
Moreover, AR regulates autophagy post-RT as AR silencing decreased autophagy-related gene (ATG) expression, and macroautophagy was augmented in LNCaP cells post-RT through LC3-II expression and ...
细胞自噬失能(Disabled macroautophagy):细胞自噬是细胞清除受损细胞器和蛋白的过程,功能异常致废物堆积,影响细胞健康。 二、拮抗标志 ...