If you have an existing Uber account: Link your MPTP card by filling out the MPTP form on the Uber website. Once verified, ...

Helping people stay connected through easy and reliable transport options is Uber's specialty, and now Multi Purpose Taxi Program (MPTP) users can use the subsidy with Uber. Travis Zimmer from ...

The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) inhibits the mitochondrial complex I of the respiratory chain. This results in ATP and ion homeostasis disturbances, which lead to selective ...

为探究 ZNRF2 在调控 mTOR 介导的神经炎症中的作用及机制，研究人员在 MPTP 诱导的帕金森病（PD）小鼠模型中开展研究。发现 ZNRF2 敲低会加重运动障碍等，抑制磷酸化 mTOR 可改善症状，揭示 ZNRF2 通过相关机制调控 PD 发病。 帕金森病（PD）给老年人群带来沉重健康 ...

本研究首次明确了： TGR5在帕金森病发病机制中的重要作用；GPS是一种有效的TGR5激动剂，可通过激活Nrf2抗氧化途径，显著改善神经元损伤和氧化应激；为开发基于TGR5的新一代抗氧化治疗药物提供了重要依据。

CA1线粒体膜通透性转换孔Mitochondrial Permeability Transition Pore（MPTP）检测试剂盒采用CA1粒体膜通透性转换孔荧光探针检线粒体膜通透性转换孔的激活情况。 线粒体膜通透性转换孔（mitochondrial permeablity transition pore，mPTP），又称线粒体巨型通道（magachannel），是存在于 ...

帕金森病（PD）由多巴胺能神经退行性变和 α- 突触核蛋白聚集引发。研究人员开展 α- 松油醇（α-TPN）对 MPTP 诱导斑马鱼胚胎 PD 模型作用的研究，发现 α-TPN 可促进发育、减轻毒性。这为 PD 及相关疾病治疗提供了新方向。 帕金森病（Parkinson’s disease，PD ...

Parkinson’s disease (PD), a progressive neurodegenerative disease, is caused by the loss of dopaminergic neurons in the substantia nigra (SN). It is characterized by the formation of intracytoplasmic ...

BACKGROUND: Dilated cardiomyopathy (DCM) is substantially influenced by genetic factors. Sarcomere function is intricately associated with other organelles, particularly the reciprocal regulation ...