AnaSpec has announced the release of three new MMP recombinant proteins, MMP-1, MMP-9 and MMP-12. These proteins, derived from the catalytic domain of the proteins, are supplied as activated proteins ...

Those affected motor neurons often show aggregation of a protein called TDP-43. The protein plays an important role in producing and stabilizing RNA, but when it misfolds and clumps together, ...

A key protein may represent a new way to use the immune system to speed healing and ... MMP-2, has another signaling role related to the human immune system. Skip to main content. Your source for ...

Purpose To determine the predictive value of urinary levels of two angiogenic factors, vascular endothelial growth factor (VEGF) and matrix metalloproteinase (MMPs), in a longitudinal study to ...

"MMP-9 is an inflammatory protein shown to be elevated in the brains of Alzheimer's patients," Cohen said. "In our study, we show that MMP-9 alone can trigger a calcium influx that floods the neuron." ...

A preclinical study shows an antibody-drug conjugate (ADC) targeting surface protein MT1-MMP can act as a guided missile in eradicating osteosarcoma tumor cells without damaging normal tissues.

Researchers at Utrecht University in the Netherlands have identified a new way in which the toxic protein aggregates associated with Huntington's disease may damage nerve cells and cause them to die.

MMP-2, or matrix metalloproteinase-2, is also called gelatinase or type IV collagenase, and belongs to a family of enzymes that break down collagens and other proteins in the extracellular matrix ...

The UNC researchers also identified two proteins -- MMP-9 and HDAC6 -- that help promote this harmful, amyloid-to-inflammation-to-tau cascade.