Taking a closer look at the mode of action Many tumor cells shift their metabolism toward glycolysis ... for one of these two transporters (MCT4). The potential application of syrosingopine ...

George Brooks proposed the “lactate shuttle” theory, which posits that lactate serves as an energy substrate, produced by cells or tissues primarily relying on glycolysis for energy ... especially ...

Biopsies of each woman’s breast cancer tumor were taken both prior to and during surgery, and the researchers analyzed them for levels of three biomarkers of cancer aggressiveness: MCT4 ...

The results, published in Seminars in Oncology, confirm a long-held theory that cancer cells are being sustained and strengthened by the presence of MCT4, a protein which 'brings them' energy ...