Abnormal kinase signaling can promote other harmful traits, such as neuroinflammation and neuronal cell death. On the other hand, the loss of function in certain kinases has been identified as a ...

Brain metastasis is emerging as the most serious concern for breast cancer patients. HER2-positive breast cancer is more prone to undergo brain metastasis than other subtypes; notably, there has been ...

Despite advancements in melanoma therapy, the prognosis remains unfavorable for many patients. The proteasome inhibitor MG132 has shown therapeutic potential through pathway regulation, yet its ...