The mechanisms underlying autophagy and its relevance both in ... intriguing questions. How does lysosome number, size and content vary in different cell types, in different tissues or in ...

Little organs within cells called lysosomes digest unwanted material. And like stomachs, they must be acidic to do so. If they aren't, cells stop growing. Researchers wanted to know why.

There are several types of vesicle, including transport ... If a cell has absorbed something harmful, such as a pathogen, it can use its lysosomes to ingest those bacteria and destroy them with ...

Next, using fluorescent dyes attached to ApoE or to its lipid cargoes, the scientists found that ... she noticed a mysterious fluorescence from their lysosomes. “If it's lysosomal, it has to be ...

He’s a biomedical researcher at Washington State University. He told me a lysosome is a specialized compartment in a cell. It’s like a little sack of digestive enzymes. Those are proteins that ...

Scientists have discovered how iron in lysosomes can induce ferroptosis, offering a new route to target treatment-resistant cancer cells and stop metastasis. Ferroptosis has been gathering an ...

Lysosomes are surrounded by a lipid bilayer ... binds to the leaky organelle and triggers its breakdown before the membrane ruptures and the survival of the cell is endangered.

Osaka University and Nara Medical University researchers reveal microautophagy's role in repairing damaged lysosomes, a breakthrough with implications for aging, cellular health, and potential ...