Using a staining method for acid phosphatase, de Duve and Novikoff confirmed its location ... we know that lysosomes contain hydrolases that are capable of digesting all kinds of macromolecules.

Thus, by the time the protein achieves its final form ... and immunity as well as membrane recycling. Lysosomes break down and thus disarm many kinds of foreign and potentially pathogenic ...

There are several types of vesicle, including transport ... If a cell has absorbed something harmful, such as a pathogen, it can use its lysosomes to ingest those bacteria and destroy them with ...

Little organs within cells called lysosomes digest unwanted material. And like stomachs, they must be acidic to do so. If they aren't, cells stop growing. Researchers wanted to know why.

Next, using fluorescent dyes attached to ApoE or to its lipid cargoes ... fluorescence from their lysosomes. “If it's lysosomal, it has to be lipofuscin,” Di Paolo recalls saying at the time. In ...

Lastly, in autophagy, the cell cleans up its own damaged parts, such as old mitochondria, by wrapping them in a membrane bubble called an autophagosome. This bubble then merges with the lysosome ...

Osaka University and Nara Medical University researchers reveal microautophagy's role in repairing damaged lysosomes, a breakthrough with implications for aging, cellular health, and potential ...

Lysosomes are surrounded by a lipid bilayer ... binds to the leaky organelle and triggers its breakdown before the membrane ruptures and the survival of the cell is endangered.

A groundbreaking anticancer treatment technology that selectively targets cancer cell lysosomes and overcomes ... This developed substance stands out for its ability to overcome drug resistance ...