胶质母细胞瘤中，此互作被证实可维持肿瘤干细胞干性。 Crosstalk between LDs and lysosomes 溶酶体通过“脂噬”（lipophagy）降解LDs，但癌症中这一过程常被劫持：肝癌细胞通过抑制ATG5依赖的巨自噬，保留LDs作为应急能源；而前列腺癌则利用分子伴侣介导的自噬（CMA ...

别 名；END1; HGNC:14583; hVPS11; PEP5; PP3476; RING finger protein 108; RNF108; Vacuolar protein sorting 11 (yeast homolog); Vacuolar protein sorting 11 (yeast); Vacuolar protein sorting 11 homolog (S.