Ferroptosis, a form of programmed cell death mediated by iron, has been a focus for its potential in cancer therapies. Now, researchers have discovered that lysosomal lipid peroxidation plays a ...

Controlled death of cells, or programmed cell death, is also necessary for the proper development and function of the body ... the lipid peroxidation of the lysosomes—the organelle responsible ...

For neurodegenerative diseases such as Alzheimer's and Parkinson's, treatment options are scant. New research by Stanford ...

Controlled death of cells, or programmed cell death, is also necessary for the proper development and function of the body. It has also been a focus of researchers ... found that the lipid ...

Controlled death of cells, or programmed cell death, is also necessary for the proper development and function of the body. It has also been a focus of researchers ... found that the lipid ...

"If the functions of some of these genes converge ... VPS13C/PARK23 mediates ER–lysosome contacts following lysosome damage, Nature Cell Biology (2025). DOI: 10.1038/s41556-025-01653-6 ...

Scientists have been searching for treatments for neurodegenerative disorders like& Alzheimer's and Parkinson's for many years... | Genetics And Genomics ...

It has a range of preclinical-stage projects that aim to harness lysosomes’ ability ... Decreased TMEM175 function reduces lysosomal efficiency in neuronal cells, and is strongly associated ...

The lab also studies mechanisms that regulate autophagy protein and lysosome function in endocytic trafficking and nutrient homeostasis. Cell biologist Michael Overholtzer explores genes that make ...

Cells from people with the disease have defects in the clearance of cholesterol molecules from the lysosome ... genetic tool with which to dissect the function of BMP in regulating lysosomal ...