BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment ...

Microglia are brain-resident macrophages playing pivotal roles in CNS development and homeostasis. Yet, the cellular and molecular basis governing microglia maintenance ...

Maternal stress is a major risk factor for preterm birth (PTB), with recent mouse studies highlighting the role of FKBP51 in stress-induced PTB. This study identifies the 15dPGJ2-mediated inhibition ...

Basic Science The esterase method of detecting leukocytes in a urine sample relies on the fact that esterases are released from lysed urine granulocytes (neutrophils). In the dipstick method ...

Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...

Center for Aerosol Science and Engineering, Department of Energy, Environmental and Chemical Engineering, Washington University in St. Louis, St. Louis, Missouri 63130, United States ...

For use with our PCR rapid detection systems, BIOTECON Diagnostics has developed fast and easy-to-use DNA extraction kits. The foodproof ® ShortPrep, StarPrep, Sample Preparation and Magnetic ...

Controlling mechanical properties of polymeric biomaterials, including the elastic modulus, is critical to direct cell behavior, such as proliferation and differentiation. Dityrosine photocrosslinking ...

Circular RNA (circRNA) is a subclass of non-coding RNAs that enables the circular transcripts resistant to the exonuclease digestion. Iron homeostasis is essential for the body to maintain normal ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Regulatory T cells (Tregs) play critical roles ...