Lung premalignant lesions (PMLs), precursors to cancer, represent an opportunity for further mortality reduction, but detection methods remain underexplored. This study uses single-cell RNA sequencing ...

The University of Hong Kong, Pokfulam, Hong Kong.

A new tissue expansion method enables scientists to use mass spectrometry imaging to simultaneously detect hundreds of molecules at the single cell level in their native locations. For biologists ...

Using a combination of cell-based and mouse models, the authors provide compelling evidence showing that arginine restriction in the microenvironment disrupts lipid homeostasis in PDAC, resulting in ...

Compared to previous omics analyses of CRC, our multi-omics classification provided deeper insights into EMT in cancer cells with stronger correlations with risk of relapse. Proteomics profiling of a ...