Lung epithelial cells are increasingly recognized to be active effectors of microbial defense, contributing to both innate and adaptive immune function in the lower respiratory tract. As immune ...

“Epithelial cells in the lung are typically envisioned as supporting respiratory functions, while MHC-II is understood to connect immune cells to immune cells, so the finding that MHC-II on lung ...

Lung cancer remains the world’s deadliest cancer, and cigarette smoke is its chief culprit. Chemicals in tobacco, such as ...

compared the chemical composition of cannabis smoke and cannabis vapor (i.e., the aerosol produced by vaping cannabis), as well as their in vitro effects on human lung epithelial cells ...

It prevents lung cells from dividing when they need to be replaced. And senescent cells secrete mediators that further promote fibrosis. Since this effect also plays a role in cancer, the ...

the part of the study where the engineered lung mesenchymal cells are combined with lung epithelial cells in culture dishes (so called "recombinants") is particularly exciting as this resulted in ...

In their second paper, "Durable alveolar engraftment of PSC-derived lung epithelial cells into immunocompetent mice," CReM researchers targeted the lung air sacks, known as alveoli. Kotton and his ...

Neurons talk to one another using electricity. If you could hear these impulses, they might sound like constant, rapid-fire ...

Alveolar epithelial type 1 cells, which line lung tissues, are crucial to the exchange of oxygen and carbon dioxide gases. And alveolar type 2 cells or (AT2s) are known to act as stem cells to ...

indicating that the lung environment supports B cell development. The findings fundamentally change the understanding of the immune and epithelial interactions that are crucial for foetal lung ...

In a Scientific Reports study, University of Alabama at Birmingham researchers show how a low dose of cadmium produces a deleterious stress in lung epithelial cells, and their findings highlight ...

Original-Publikation: Lehmann, M. et al. (2017): Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosis ex vivo. European Respiratory Journal ...