Epigenetic modifications include methylation, histone modifications, and non-coding RNAs disturbances (59). Oncogene promoters can be demethylated and subsequently gene expression is elevated ...

Non-coding RNAs (ncRNAs) are RNA molecules that do not encode proteins but are involved in dynamic cellular regulatory ...

Long non-coding RNAs (lncRNA ... and have been implicated in several cellular functions, including the regulation of gene transcription through the recruitment of chromatin-modifying enzymes.

The startup’s first prospect is a heart medicine that works differently than the hypertrophic cardiomyopathy drugs developed ...

Exosome non-coding ... Results RNA sequencing identified 182 candidate biomarkers for GC, of which 31 were validated as potential biomarkers by qRT-PCR. The combined diagnostic score (cd-score), ...

But researchers have long suspected ... precise exploration of RNA-based gene regulation and could one day help scientists better understand and even control gene expression in diseases.

"It rather modulates how information is processed at the RNA level—a more subtle but potentially powerful form of gene regulation." These insights contribute to a growing understanding of how ...

It is the first big biopharma group to tap into Haya's platform, which identifies genes coding for long non-coding RNA ... which often involve control of gene expression and the regulation ...

These lncRNAs influence a wide range of cellular processes, including the regulation of gene expression ... and metastasis. Long non-coding RNAs (lncRNAs), a class of non-coding RNAs longer ...

Long non-coding RNAs (lncRNAs ... including gene expression and immune cell function. This review explores the multifaceted roles of lncRNAs in modulating the immune microenvironment of HCC. We ...