By Dr. Sushama R. Chaphalkar, PhD. Mutations in LXRα lead to liver cholesterol buildup, hepatitis, and fibrosis in ...

Liver X receptors belong to a family of genes called nuclear receptors, according to Lin. Their functions involve regulating metabolism and the transportation of cholesterol.

Cholestatic liver diseases (CLDs) are a group of disorders characterized by the impairment of bile formation, secretion, or ...

Metabolic dysfunction-associated steatotic liver disease (MASLD), affecting approximately 30% of the global population, ...

Metabolic dysfunction-associated steatotic liver disease (MASLD), affecting approximately 30% of the global population, ...

In patients with metabolic-associated steatotic liver disease or metabolic-associated steatohepatitis, resmetirom and ...

Activation Of Liver X Receptor-Beta Lowers Cholesterol And Reverses Atherosclerosis Date: July 30, 2007 Source: Journal of Clinical Investigation Summary: A new study shows that activation of LXR ...

Liver X receptors (LXRs) are nuclear receptors that function as intracellular cholesterol sensors, orchestrating a complex network of genes involved in lipid metabolism, cholesterol homeostasis ...

Adding bile acids as farnesoid X receptor agonists to the culture medium supported the growth and development of unique stem ...