Primary sclerosing cholangitis, PSC in short, is a rare liver disease that destroys the bile ducts. It is a severe condition ...

PARIS, France I June 10, 2025 I As metabolic dysfunction-associated steatohepatitis (MASH) emerges as one of the most dangerous and underdiagnosed drivers of ...

Hepatitis C virus (HCV) infection is highly associated with the development of metabolic dysfunction-associated steatotic ...

Find more information on the Altmetric Attention Score and how the score is calculated. Tertiary sulfonamides were identified in a HTS as dual liver X receptor (LXR, NR1H2, and NR1H3) ligands, and the ...

Weight-loss drugs like Ozempic and Wegovy are used by more than 15 million adults in the U.S., or 4.5% of the population.

Background Current treatments with tyrosine kinase inhibitors and immune checkpoint inhibitors have limited efficacy for ...

Improves fibrosis and steatohepatitis Metabolic dysfunction-associated steatotic liver disease (MASLD) encompasses a broad clinical spectrum, ranging from simple steatosis to metabolic ...

New licensing agreement with Hansoh Pharma provides Regeneron with HS-20094, a GLP-1/GIP receptor agonist in advanced stages of clinical development in China ...

The study led by Professor Jan-Åke Gustafsson and colleagues at the University of Houston and Karolinska Institutet demonstrated that liver X receptors (LXRs) and thyroid hormone receptors (TRs ...

Study: Therapeutic potential of liver X receptor beta in depression and anxiety. Image Credit: peterschrieber.media / Shutterstock.com In a recent review published in the journal Brain Medicine ...

A recent review highlights the potential of liver X receptor beta (LXRβ) as a target for treating depression and anxiety. Known for regulating cholesterol, LXRβ is emerging as a key player in mental ...