The peptide Palmitoyl-GHK (Pal-GHK) has garnered considerable attention in the scientific community due to its structural attributes and potential functional roles in biological research and cellular ...

A new class of lipids developed by Penn Engineers improve the rates at which lipid nanoparticles (LNPs) successfully deliver ...

Here, we use a synthetic amphiphile to modulate the membrane mechanical properties of cell-derived vesicles and probe channel activation. Using precise membrane mechanical characterization approaches ...

Proteins are life's engines, powering processes like muscle movement, vision, and chemical reactions. Their environments—water, lipid membranes, or other condensed phases—are critical to their ...

An interview on how advanced techniques can be used to enhance silk fibroin and chitosan for drug delivery applications.

Integral membrane proteins carry out essential functions in the cell, and their activities are often modulated by specific protein-lipid interactions in the membrane. Here, we elucidate the intricate ...

Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, Tennessee 37996, United States Center for Molecular Biophysics, University of Tennessee/Oak Ridge ...

ApoB-100’s massive size and association with lipids in LDL have frustrated conventional approaches to studying its detailed structure. Berndsen and Cassidy and Reimund et al. have overcome this ...

Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, ...