P2Rank: Protein-ligand binding site prediction from protein structure based on machine learning.

The strength of theoretical approaches is in the simplification of complex biological systems. We here consider the general problem of receptor–ligand binding in the context of antibody–antigen ...

Researchers from Southwest Jiaotong University published the discovery of novel high affinity peptides against the protein of human DNA binding domain of FOXM1 (FOXM1-DBD) to be developed for the ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. ABCB1 is a broad-spectrum efflux pump central ...

Ubiquitin-binding domains (UBDs) are modular elements that bind non-covalently to the protein modifier ubiquitin. Specific ubiquitin–UBD interactions are crucial for the regulation of multiple ...

(D) Histogram shows the binding free energies for HS-H3 interactions in motifs 1, 2, 3, and the helical domain. (E) A free energy landscape map from a 1000 ns REMD simulation shows HS binding ...

Golfers at the Atlantic Beach Links, situated 700m from the beach in Melkbosstrand, Cape Town, were treated to a spectacular ...

After hours: January 31 at 4:20:00 PM EST Loading Chart for LGND ...

Our work has generated investment ideas in health care, consumer electronics, finance technologies, transportation, AI-based Oppenheimer raised the firm’s price target on Ligand (LGND ...

Ligand Pharmaceuticals Incorporated, a biopharmaceutical company, engages in the development and licensing of biopharmaceutical assets worldwide. Its commercial programs include Kyprolis and ...