A 3 year-old girl presented with progressive spasticity, visual loss and loss of motor milestones. Metachromatic Leukodystrophy (MLD): Flair axial MRI images. Note the bilateral confluent white matter ...

Gait changes can occur, as well as seizures and bladder dysfunction. This is an autosomal dominant disorder, but the penetrance is incomplete and cases with de novo mutations have been reported in the ...

Synchronization between a wearer and a lower limb powered prosthesis is important for effective control. Typically, phase variable-based phase estimation methods are employed. However, there is a ...

Researchers have identified an early postnatal window that allows gene transfer to circulating blood stem cells, advancing the development of potential treatments for genetic disorders. A team of ...

Background Abnormal biomechanics have been cited as a potential risk factor for running-related injury. Many modifiable biomechanical risk factors have also been proposed in the literature as ...

Gait analysis also helps clinicians determine primary and secondary gait pathologies. This means gait problems directly caused by a person’s condition versus those generated by methods they use to ...

A team of scientists from the San Raffaele-Telethon Institute for Gene Therapy (SR-Tiget) in Milan, Italy, has identified a unique window shortly after birth in which circulating blood stem cells ...