The colocalisation with laminin indicates a mechanism of interaction between smooth muscle cells and mast cells that may be important in the role of mast cells in the process of fibrosis. Fibrosis and ...

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Introduction: Spinal cord injury involves complex pathobiological mechanisms, necessitating a multidimensional approach for its cure. Previous studies have shown that α9-integrin expression and ...

Introduction: Dystroglycan (DG) is an adhesion complex comprising two subunits, α-DG and β-DG, which interact non-covalently at the plasma membrane. As a component of the dystrophin-glycoprotein ...

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结果发现 FAP+ CAFs 可诱导巨噬细胞向 M2 样极化，且 FN1-Integrin α5β1 轴或可成治疗靶点，意义重大。 表达成纤维细胞激活蛋白（FAP + ）的癌相关成纤维细胞（cancer-associated fibroblasts，CAFs）是乳腺癌微环境的关键调节因子，但其免疫调节机制尚不清楚。通过单细胞 ...

Most studies have focused on anti-laminin 332 MMP, despite it being a minority among MMP patients.” 1 The researchers noted that increased autoimmunity, a possible factor in cancer risk ...

Over the past two decades, the role of vitreomacular adhesion in vitreomacular interface pathologies, such as vitreomacular traction syndrome, epiretinal membrane and macular hole, has been ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Rheumatoid arthritis (RA) is associated with ...

B) Representative image of crystal violet-stained attached cells on collagen-I or laminin coated plates. 200 µm scale bar ... One could trace this PASMC susceptibility to ECM composition change to ...