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Depletion of SUN1/2 诱导间充质干细胞成脂过程中异染色质积累:LINC 复合 ...
为探究破坏 LINC 复合体介导的细胞骨架连接对染色质组织和间充质干细胞(MSC)分化的影响,研究发现 SUN1/2 缺失抑制成脂,dnKASH 加速成脂,二者机制不同。 在细胞的微观世界里,间充质干细胞(MSC)的分化调控一直是生命科学领域的研究热点。其中,LINC ...
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