Lactate can also be converted to lactoyl-CoA, which is involved in the lactylation of histone and non-histone proteins. HK-1, hemokinin-1; G6PD, glucose 6-phosphate dehydrogenase; PKM, glycolytic ...

Tumor cells altered metabolism by increasing glucose uptake and fermentation of glucose to lactate, even in the aerobic state and the presence of functioning ... Normally, glucose is processed by ...