A recent study by Agudelo and colleagues 1 suggests that kynurenine metabolism in skeletal muscle mediates resilience to stress-induced behavior associated with psychiatric illnesses such as major ...

They hypothesize that that the kynurenine pathway is overactivated as a result of amyloid plaque and tau proteins that accumulate in the brains of patients with Alzheimer's disease. Now ...

Researchers have studied the biological processes that drive depression in adults and shown a potential role for the kynurenine pathway, but this is the first time it has been investigated in ...

They hypothesize that that the kynurenine pathway is overactivated as a result of amyloid plaque and tau proteins that accumulate in the brains of patients with Alzheimer’s disease. Now ...

KATs convert a substance formed during stress (kynurenine) into kynurenic acid, a substance that is not able to pass from the blood to the brain. The exact function of kynurenine is not known ...

Dario Vitturi, Ph.D., Assistant Professor, Molecular and Cellular Pathology, has received grant funding to support his project “Kynurenine-dependent redox signaling at the interface between innate and ...

Kynexis BV recently launched with a series A of €57 million (US$62 million) and a lead asset, Kyn-5356, that targets the kynurenine pathway. The company is preparing for clinical trials that will test ...