Traditional approaches to biologics production?relying on one-size-fits-all expression vectors and empirical process optimization?have led to inefficiencies in expression, scalability and ...

We used cDNA microarrays to explore the variation in expression of approximately 8,000 unique genes among the 60 cell lines used in the National Cancer Institute's screen for anti-cancer drugs.

Adagrasib shows early signs of activity and tolerability in patients with STK11/KRAS G12C–mutated non–small cell lung cancer. The ORR appeared numerically higher in ... Consistent with prior reports, ...

Among 7 patients with PD-L1 expression greater than or equal to 50% ... Negrao MV, He K, Yau E et al. Adagrasib (ADA) as first-line therapy in patients (pts) with advanced non-small cell lung cancer ...

Eli Lilly and Company today announced that data from studies of imlunestrant, an investigational oral selective estrogen receptor degrader (SERD), olomorasib, an investigational KRAS G12C inhibitor, ...

We're so excited to share the most significant achievement of our study: we've successfully connected wireless electromagnetic controls to natural transgene expression in mammalian cells via ...

Amgen has its first direct competition in the KRAS inhibitor class ... to plan a phase 3 trial as a first-line NSCLC therapy in patients with low PD-L1 expression. While going after a PD-L1 ...

Additionally, there is a growing trend towards developing TCR-CAR hybrids to enhance the effectiveness of T-cell therapies. 1 These advancements require the expression of T cell-related proteins ...

Clinicians and scientists from RWJBarnabas Health and Rutgers Cancer Institute will share new findings and lead discussions ...

Cytokine secretion expression (IFN-γ and IL-2) were measured by an enzyme-linked immunosorbent assay. HEK293T, RT4, SW780, 5637, U87-MG, HGC-27, MDA-MB-231, SW620, ES-2, SKOV-3, and HOS cells were ...

Data presented at American Association for Cancer Research (AACR) Annual Meeting. In April 2025, Foghorn presented new preclinical data highlighting pipeline progress for potential first-in-class ...