Compared to traditional kallikrein activity assays that use the enzyme in solution with fluorimetric detection, the proposed method offers several advantages. It allows for enzyme reuse, reducing ...

研究结果 RNAi 筛选确定 Klk8 为候选蛋白酶：研究人员通过 RNAi 筛选发现，Kallikrein-8（Klk8）在黑色素瘤细胞中能够介导不依赖弗林蛋白酶（furin）的 Activin-A 前体半切割过程，生成 A70 中间产物。敲低 Klk8 可抑制 A70 形成及 Activin-A 诱导的信号传导，这表明 Klk8 在 ...

H.C. Wainwright analyst Matthew Caufield raised the firm’s price target on DiaMedica Therapeutics (DMAC) to $10 from $7 and keeps a Buy rating ...

Patients with hereditary angioedema whose attacks impacted their larynx experienced on-demand relief within 1.29 hours with ...

Q4 2024 Earnings Call Transcript March 18, 2025 Operator: Good morning, ladies and gentlemen, and welcome to the DiaMedica ...

Introduction: The complement and kallikrein-kinin systems (KKS) are both activated during vascular inflammation, and there are many known interactions between the two systems. This study investigated ...

DiaMedica Therapeutics Inc.’s DMAC share price has dipped by 13.02%, which has investors questioning if this is right time to buy.

Astria Therapeutics, Inc.’s ATXS share price has surged by 10.36%, which has investors questioning if this is right time to ...

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Here the authors identify that kallikrein-8 mediates furin-independent cleavage of Activin-A precursor to promote tumor growth in a murine melanoma model.