Serum was analyzed for anti-insulin antibody, islet-cell antibody 512, and glutamic acid decarboxylase antibody before and after transplantation. 19 Mean serum anti-insulin antibody concentrations ...

Tuesday, June 3, 2025. News & Perspective Drugs & Diseases CME & Education Video Decision Point Drugs & Diseases CME & Education Video Decision Point ...

The findings, published on June 24 in Cell Stem Cell, could allow physicians to treat more patients with fewer cells. In type 1 diabetes, autoimmune cells attack the pancreatic islets, destroying ...

Groundbreaking First-in-Human Study Establishes Potential to Treat Type 1 Diabetes by Transplanting Insulin-Secreting Cells Without Immunosuppression ...

USA: People diagnosed with celiac disease or thyroid disorders may be at significantly increased risk of developing type 1 ...

Although autoantibodies occur in healthy individuals, pathogenic autoantibodies are the key etiologic agent in many autoimmune diseases in humans, most notably lupus erythematosus. In this Review ...

Lead amylin receptor agonist engineered antibody significantly reduced acute food intake in a mouse model of obesity, ...

·Evidence of islet autoimmunity (e.g., islet cell [ICA] 512 or IA-2, GAD, and insulin autoantibodies) · Evidence of ß-cell secretory capacity (e.g., C-peptide levels) after 1 year, if diagnosis ...

Get Instant Summarized Text (Gist) A membrane protein, FXYD2, has been identified as a marker that distinguishes functional, mature stem cell–derived islet organoids from non-functional ones.

One-year results from the company's FORWARD-101 trial of islet cell therapy zimislecel (also known as VX-880) showed that all ...

Two biomarker tests -- one for blood and the other for stool -- are mainstays in the treatment of inflammatory bowel disease ...