A Trypanosomatid Iron Transporter that Regulates Mitochondrial Function Is Required for Leishmania amazonensis Virulence. PLOS Pathogens , 2016; 12 (1): e1005340 DOI: 10.1371/journal.ppat.1005340 ...

Citation: Mittra B, Laranjeira-Silva MF, Perrone Bezerra de Menezes J, Jensen J, Michailowsky V, Andrews NW (2016) A Trypanosomatid Iron Transporter that Regulates Mitochondrial Function Is ...

Iron is an essential nutrient but, in high concentrations, it is also toxic to cells. Here, Slavic et al. identify an iron transporter in malaria parasites that plays a major role in iron ...

And if we completely remove this iron transporter in the beta cells in genetically engineered mice, they are indeed protected against diabetes," explains Professor Thomas Mandrup-Poulsen, ...

Iron-binding activity of FutA1 subunit of an ABC-type iron transporter in the cyanobacterium Synechocystis sp. strain PCC 6803. Plant Cell Physiol 42 : 823–827. Article CAS PubMed Google Scholar ...

Anemia of chronic disease, the anemia that is the second most prevalent after anemia caused by iron deficiency, occurs in patients with acute or chronic immune activation. 1–4 The condition has ...

The iron supply to the cells is controlled by the two proteins IRP-1 and IRP-2. If the cell lacks iron, IRP-1 and IRP-2 crank up the production of the various iron transporter proteins that take ...

Research into the ways in which crops derive micronutrients from the soil could make it possibly to engineer higher-yield, nutrient-rich crops in poor quality soils and increase biomass in soils ...

Scientists know that two proteins, called IRP-1 and IRP-2, regulate cells' iron supply. These proteins increase the levels of iron transporters that move iron into the cell, and when iron levels are ...

Regulatory T-cells were subjected to depletion of the major iron transporter transferrin receptor 1 (TfR1) to examine the effect of an iron deficiency on immune tolerance and regulatory T-cells.

New iron transporter discovered in cereal-associated bacteria Dr. Michael Ramm Pressestelle Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie - Hans-Knöll-Institut (HKI) ...

Cartoon depicting iron metabolism in macrophages, NF-κB activation via TLR2 signaling enhances Lipocalin 2 (LCN2) production which enhances uptake of extracellular iron into macrophages, labile ...