研究人员进行了多项测试以确认 dCK 敲低是否促进辐射诱导的铁死亡。正如预期的那样，与对照组相比，dCK 敲低的 HeLa 细胞内 Fe2+浓度显著升高；这种效应可能因辐射治疗而增强。然后，与 shControl 相比，经辐射或厄拉司汀处理后，通过 BODIPY C11 染色检测到的 dCK 敲低 HeLa 细胞的脂质过氧化显著增加，而这一现象可通过 Fer-1 ...

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