Large-scale microscopy combined with tissue clearing and expansion enables nanoscale imaging of centimeter scale specimens.

Primo Vert Inverted Microscope from Zeiss. Sigma Field Emission Scanning Electron Microscopes from Carl Zeiss. SteREO Discovery.V12 Stereo Microscope from Carl Zeiss.

Get Instant Summarized Text (Gist) A deformable X-ray mirror made from a single-crystal lithium niobate wafer enables beam size adjustment by over 3,400 times, surpassing traditional two-part mirrors.

This meant that a microscope could not resolve two objects located closer than λ/2NA, where λ is the wavelength of light and NA is the numerical aperture of the imaging lens.