The extracellular matrix protein fibronectin forms fibrils when in association with cells that exert tension. Cells apply enough force to stretch fibrils in vivo. Stretching of individual ...

This study highlights lumican as a promising biomarker for predicting the onset and progression of diabetic nephropathy and reveals its close association with extracellular matrix remodeling, a ...

University of Nebraska Medical Center, Omaha, NE. Search for other works by this author on: ...

EGFR-EVs: promoting tumour growth and metastasis through dendritic cells and cytokines. EGFR activates the PI3K-AKT pathway, upregulating matrix metalloproteinases (MMPs), leading to tumour invasion, ...

ADAMTS5 functions like a pair of scissors by cleaving proteins within the extracellular matrix (ECM), the tissue ... ADAMTS5 controls ovarian cancer cell invasion, downstream of Rab25, The FEBS ...

Postgraduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.

These findings highlight the importance of matrix component interactions in modulating detection sensitivity and show that these effects are critical in allowing clinically relevant detection levels ...

Dr Olwyn Mahon on how she uses 3D models to understand tumour behaviour in urological cancers and why translating lab work to ...

Once considered a waste product of cells, researchers now understand the health implications of extracellular vesicles. "Beneficial cargo within these transporters—proteins, for instance—aid ...

"It's like, I really don't have it that bad in terms of invasion of privacy, you know what I mean?" Abrams said. "I feel like I learned a lot from her, obviously, but one of the things that I've ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Colorectal cancer molecular signatures derived ...